Mercedes GLS 450 vs GLE 450: Full Comparison

May 15th, 2026 by

 

Shoppers in Florence, SC often compare the Mercedes-Benz GLE 450 and GLS 450, both powered by a turbocharged inline-6 with EQ Boost mild-hybrid technology. While both deliver premium performance and advanced tech, they differ in size, space, and overall value.

This guide from Mercedes-Benz of Florence breaks down performance, comfort, and fit to help drivers in Florence, Darlington, Sumter, Hartsville, and Conway choose between midsize and full-size luxury SUVs. Compare both models or schedule a test drive today.

GLE 450

 

Overview

This comparison from Mercedes-Benz of Florence helps drivers evaluate key differences in size, space, ride quality, and overall luxury experience—making it easier to choose between a midsize SUV and a full-size flagship model.

Here’s a quick side-by-side breakdown:

 

Category GLE 450 GLS 450
Size Midsize SUV (~194 in length) Full-size SUV (~205 in length)
Seating 5 standard / up to 7 optional 7 standard (3 rows)
Cargo Space ~75 cu ft max ~85 cu ft max
Engine 3.0L turbo inline-6 + EQ Boost 3.0L turbo inline-6 + EQ Boost
Power ~375 hp ~375 hp
0–60 MPH ~5.5–5.8 sec ~5.8–6.1 sec
MPG (Est.) ~21–24 combined ~19–22 combined
Driving Feel Sportier, more agile (~39 ft turning) Smoother, more refined (~42 ft turning)
Best For City driving, smaller families Large families, road trips

 

 

Price & Value Comparison

The Mercedes-Benz GLE 450 typically starts around $63,000–$66,000 MSRP, while the GLS 450 begins closer to $88,000–$92,000 MSRP. The GLE offers strong value in the midsize luxury segment, while the GLS commands a higher price due to its larger size, added space, and flagship positioning in the Mercedes-Benz SUV lineup. Buyers in Florence and Sumter will see the price difference reflect overall capability, comfort, and interior room.

Call our team 854-400-3208 for accurate pricing and to compare current offers at Mercedes-Benz of Florence to find the best fit for your budget.

 

Which One Should You Choose?

 

Choose based on your lifestyle needs and how much space and luxury you want day-to-day.

  • GLE 450: Best for balanced luxury, easier driving, and everyday use
  • GLS 450: Best for maximum space, true 3-row comfort, and flagship luxury feel
  • GLE advantage: More maneuverable and typically lower monthly cost
  • GLS advantage: More passenger room, cargo space, and premium ride comfort
GLS 450

 

Why Shop Mercedes-Benz SUVs with Us?

Mercedes-Benz of Florence serves as the region’s source for luxury SUVs, just a short drive from Darlington, Sumter, Hartsville, and Conway. Here, you can compare the latest GLE 450 and GLS 450 side by side—explore available colors, trims, and luxury features. Expect a strong inventory, flexible financing and lease options, and expert guidance.

Visit Mercedes-Benz of Florence or browse our extensive SUV selection online to start your luxury journey today.

 

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